“Virus says what is this you know evolution has not prepared me throughout tens of millions of years to be able to infect and deliver dnas to the cells successfully so we invented a technology that enabled us to reprogram these viruses and make them much better at carrying that Dna to a variety of cells and tissues throughout the body. Yeah, basically adapted a ah protein engineering approach called directed evolution that was emerging in the field at the time and actually went on to win the nobel prize in 2018 and we were the first to use that with aav and with gene therapy.”