Longwood Fund

Portfolio Companies 2026 for Longwood Fund: investors, rounds, and co-investor patterns from StartupFundraising.com research, updated for 2026.

Longwood Fund accounts for 22 tracked companies with verified cap-table data, 22 of which disclose round sizes totalling $3.3B. The median disclosed raise is $115M, and the largest is Avenzo Therapeutics at $446M, ahead of Pyxis Oncology ($326M) and Tome Biosciences ($213M).

The names that recur most often on these portfolio cap tables are Longwood Fund (22 companies), RA Capital Management (5 companies), Alexandria Venture Investments (5 companies), Pfizer Ventures (4 companies), Novartis Venture Fund (4 companies), Alta Partners (4 companies). By latest disclosed round, the market skews Series A (13), Series B (4), Series C (3), IPO (1).

Best funded Longwood Fund companies

  1. Avenzo Therapeutics — $446M (latest: Series A)
  2. Pyxis Oncology — $326M (latest: IPO)
  3. Tome Biosciences — $213M (latest: Series B)
  4. Crystalys Therapeutics — $205M (latest: Series A)
  5. Aristea Therapeutics — $205M (latest: Series A)
  6. AAVantgarde Bio — $202M (latest: Series B)
  7. BridgeBio Oncology Therapeutics — $200M (latest: Growth)
  8. Mediar Therapeutics — $181M (latest: Series A)
  9. TScan Therapeutics — $180M (latest: Series C)
  10. Sidewinder Therapeutics — $162M (latest: Series B)
  11. Evommune — $115M (latest: Series C)
  12. ImmuneID — $113M (latest: Series A)
  13. Rectify Pharmaceuticals — $100M (latest: Series A)
  14. Newleos Therapeutics — $93M (latest: Series A)
  15. Renovia — $91M (latest: Series C)

Longwood Fund — related firms and companies (56)

Longwood Fund profile · All research reports