Millie Liu is the Co-Founder and Managing Partner of First Star Ventures. See sector focus and contact routes.
Millie Liu is the Co-Founder and Managing Partner of First Star Ventures, a Boston-based venture capital firm she established in 2014 after working as a business consultant and co-founding an MIT startup that became the AI healthcare platform Infervision. Her investment thesis targets early-stage “computing × real-world” startups in sectors including Techbio, life sciences, AI, robotics, and enterprise tech, focusing exclusively on pre-seed and seed rounds in the Boston and Cambridge geographies. The firm typically writes checks between $100K and $1M, with a sweet spot around $1M, and Liu often participates as a lead investor given her role as a founding partner. Notable portfolio companies include Extellis and Bedrock Energy, which received recent investments from First Star in 2025, alongside Infervision, the AI precision healthcare company she co-founded before joining venture capital. A distinctive point of view Liu and her firm uphold is a strict “rebuildability bar,” refusing to invest unless the technology cannot be recreated by 3–5 Google engineers within 3–12 months, ensuring genuine defensibility. Liu also serves on the advisory board of MIT’
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