What does 645 Ventures invest in?

645 Ventures (New York, New York, United States) — sector focus: Online, Healthcare.

How do I contact 645 Ventures?

645 Ventures's published profile links (website, LinkedIn or X where available) are listed on the StartupFundraising.com investor profile.

Where is 645 Ventures headquartered?

645 Ventures is based in New York, New York, United States.

645 Ventures — Venture Capital in New York

About 645 Ventures

645 Ventures is an early-stage venture capital firm founded in 2013 by Aaron Holiday and Nnamdi Okike, based in New York City and San Francisco with over $550 million in assets under management. The firm invests primarily in Seed, Series A, and Series B rounds across enterprise software, SaaS, developer tools, fintech, healthcare, and commerce, with a geographic focus on North America. Typical check sizes range from $1 million to $20 million, and the firm often acts as a lead or co-lead investor. Notable portfolio companies include RentSpree, Aryeo, Efficient Capital Labs, AppLovin, JUUL, and Calm. A distinctive aspect of 645 Ventures is its data-driven approach powered by a proprietary software platform called Voyager, which it uses to identify high-potential startups through thematic research and metrics. The firm emphasizes four founder paradigms—purity of motivation, earned secret, obsessed problem solving, and non-consensus thinking—as part of its research-driven investment philosophy.

645 Ventures at a glance

Location: New York, New York, United States
Investor type: Venture Capital
Focus areas: Online, Healthcare

Frequently asked about 645 Ventures

What does 645 Ventures invest in?: 645 Ventures (New York, New York, United States) — sector focus: Online, Healthcare.
How do I contact 645 Ventures?: 645 Ventures's published profile links (website, LinkedIn or X where available) are listed on the StartupFundraising.com investor profile.
Where is 645 Ventures headquartered?: 645 Ventures is based in New York, New York, United States.

StartupFundraising tracks this firm record from SEC filings and announced rounds, updating focus, location and portfolio history as new data lands. Use it to gauge fit before an outreach, then widen the search to investors in New York.

645 Ventures

About 645 Ventures

645 Ventures at a glance

Frequently asked about 645 Ventures

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