Most Backed South San Francisco, CA Startups 2026

8 South San Francisco, CA startups ranked by number of verified backers, led by Stripe, Addition Therapeutics, Maze Therapeutics.

South San Francisco, CA accounts for 84 tracked companies with verified cap-table data, 84 of which disclose round sizes totalling $18B. The median disclosed raise is $105M, and the largest is Vaxcyte at $2.4B, ahead of Freenome ($1.1B) and Verily ($1B).

The names that recur most often on these south san francisco, ca cap tables are Alexandria Venture Investments (10 companies), Cormorant Asset Management (7 companies), Versant Ventures (7 companies), The Column Group (6 companies), Omega Funds (6 companies), Third Rock Ventures (6 companies). By latest disclosed round, the market skews Series A (28), Series B (17), Series C (12), IPO (7).

Best funded South San Francisco, CA companies

  1. Vaxcyte — $2.4B (latest: IPO)
  2. Freenome — $1.1B (latest: Growth)
  3. Verily — $1B (latest: Growth)
  4. ORIC Pharmaceuticals — $900M (latest: IPO)
  5. Angion Biomedica — $900M (latest: IPO)
  6. Annexon Biosciences — $634M
  7. Alumis — $529M (latest: Series C)
  8. Race — $500M (latest: Growth)
  9. Plenty — $500M (latest: Series D)
  10. Nkarta Therapeutics — $404M (latest: IPO)
  11. Glydways — $395M (latest: Series C)
  12. Denali Therapeutics — $349M (latest: Series A)
  13. Genesis Therapeutics — $300M (latest: Series B)
  14. NGM Bio Holdings — $257M (latest: Series A)
  15. Pliant Therapeutics — $251M (latest: IPO)

More South San Francisco CA research (1)

Research on comparable markets (18)

Sector × city funding reports (20)

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