Most Active Biotech Investors 2026

21 firms ranked by verified Biotech deal count, led by Alexandria Venture Investments, ARCH Venture Partners.

Biotech accounts for 120 tracked companies with verified cap-table data, 120 of which disclose round sizes totalling $58B. The median disclosed raise is $279M, and the largest is Metsera at $10B, ahead of Revolution Medicines ($2.1B) and Kailera Therapeutics ($1.6B).

The names that recur most often on these biotech cap tables are ARCH Venture Partners (14 companies), RA Capital Management (14 companies), OrbiMed (13 companies), Foresite Capital (12 companies), Atlas Venture (10 companies), Fidelity Management & Research Company (9 companies). By latest disclosed round, the market skews Series B (26), Series A (20), Series C (18), Series D (18).

Best funded Biotech companies

  1. Metsera — $10B (latest: IPO)
  2. Revolution Medicines — $2.1B (latest: IPO)
  3. Kailera Therapeutics — $1.6B (latest: IPO)
  4. Neuralink — $1.3B (latest: Series E)
  5. Kriya Therapeutics — $1.2B (latest: Series C)
  6. Treeline Biosciences — $1.1B (latest: Series A)
  7. 23andMe — $1B (latest: IPO)
  8. Beam Therapeutics — $1B (latest: IPO)
  9. Xaira Therapeutics — $1B (latest: Series A)
  10. Oruka Therapeutics — $975M (latest: IPO)
  11. ORIC Pharmaceuticals — $900M (latest: IPO)
  12. Recursion Pharmaceuticals — $900M (latest: IPO)
  13. Generate Biomedicines — $750M (latest: IPO)
  14. Odyssey Therapeutics — $726M (latest: Series D)
  15. Astria Therapeutics — $700M (latest: Growth)

More Biotech research (2)

Research on comparable markets (14)

Sector × city funding reports (20)

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•By Alejandro Cremades