Christoph Westphal is the Co-Founder and General Partner of Longwood Fund. See sector focus and contact routes.
Christoph Westphal is the Co-Founder and General Partner of Longwood Fund, an early-stage healthcare venture capital firm in Boston, MA, where he leverages over 20 years of experience as a biotech CEO, entrepreneur, and investor. His investment thesis centers on incubating early-stage biotechnology companies to develop novel therapeutics for severe diseases, focusing exclusively on life sciences, biotechnology, therapeutics, and drug discovery within the United States. Longwood Fund operates a distinctive company-creation model rather than traditional external investing, having founded over 20 life sciences companies to date with Westphal managing $750 million in assets. Notable portfolio companies resulting from this model include Alnylam Pharmaceuticals, Acceleron Pharma, Sirtris Pharmaceuticals, and Pyxis, all of which he co-founded or led. Westphal’s distinctive point of view emphasizes creating sustained market value through FDA-approved drugs, having personally led seven biotech IPOs generating over $70 billion in market value and securing approvals for over 10 important drugs, including the first RNA medicines. He holds an MD from Harvard Medical Scho
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