Mark DePristo, Founder of BigHat Biosciences

About Mark DePristo

Mark DePristo is the co-founder and founding CEO of BigHat Biosciences, an AI-first antibody design company he launched in 2019. He led the company from seed to Series B, raising over $130M from investors. He stepped down from the CEO role in March 2025.

Mark DePristo at a glance

• Company: BigHat Biosciences
• Total raised: $130M
• Investors: Section 32, Andreessen Horowitz, 8VC
• Location: Silicon Valley, United States

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