Cary Pfeffer, a Partner at Third Rock Ventures, invests in early-to-mid-stage life sciences and biotechnology companies. See sector focus and contact routes.
Cary Pfeffer, a Partner at Third Rock Ventures, invests in early-to-mid-stage life sciences and biotechnology companies, focusing on novel drug discovery, gene and cell therapies, immunology, oncology, and neuroscience[1][11]. His recorded investments include Series A and B rounds typically ranging from $12M to $81M, with a personal sweet spot around $1.5M and an investment range of $100K–$5.0M[2]. Notable portfolio companies he has helped launch or lead include Jounce Therapeutics (cancer immunotherapy), Neon Therapeutics (immuno-oncology), Rheos Medicines (immunometabolism), and TARIS Biomedical, where he joined the board[5][7][9][10]. Pfeffer’s distinctive thesis aligns with Third Rock’s “Discover-Launch-Build-Transform” model, which actively shapes company strategy from inception rather than investing in pre-formed entities[11].
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