Steve Komie is the founder and managing director of Harbor Street Ventures. See sector focus and contact routes.
Steve Komie is the founder and managing director of Harbor Street Ventures, a Chicago-based family office he established in 2014 that deploys its own capital into early-stage ventures. The firm’s investment thesis targets seed to Series A companies primarily within the healthcare sector, with specific focus on health technology, medical devices, and life sciences. While the firm has made only seven investments total, it typically engages at the seed stage and provides strategic guidance rather than specifying a fixed check size or lead/follow role. A notable portfolio company is Enzee Health, which received a seed venture capital investment from Harbor Street in September 2022. The firm also expresses interest in game-changing devices, new materials, and novel artificial intelligence applications, though these appear secondary to its core healthcare focus. No public writing or distinctive point of view by Komie himself is documented in the available sources, and the firm’s small portfolio limits the number of other named companies.
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