Zane Lackey is a General Partner at Andreessen Horowitz (a16z). See portfolio, sector focus and contact routes.
Zane Lackey is a General Partner at Andreessen Horowitz (a16z), where he leverages two decades of experience as a founder and security leader, having co-founded Signal Sciences and served as Etsy’s first Chief Information Security Officer [1][2][7]. His investment thesis centers on modern DevOps, DevTools, cybersecurity, and enterprise infrastructure, targeting companies from seed through Series B rounds [2][5][9]. He writes checks ranging from $10,000 seed bets to $100 million growth rounds, participating across both early and late stages [3][9]. Notable portfolio companies include Noetic AI, an anomaly-detection platform for security teams, and Signal Sciences, which he founded and was later acquired by Fastly [2][9]. Lackey’s distinctive point of view stems from his hands-on hacking background and operational security experience at high-growth companies like Etsy, giving him a founder-centric perspective on building secure infrastructure [7]. He frequently publishes on a16z’s author page focusing on cybersecurity and enterprise technology trends [5].
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