Nick Naclerio, Ph.D., is the Founding Partner of Illumina Ventures. See sector focus and contact routes.
Nick Naclerio, Ph.D., is the Founding Partner of Illumina Ventures, a venture capital firm he established in 2016 to build companies at the intersection of technology and human health. Prior to founding the fund, he served as SVP of Corporate & Venture Development at Illumina Inc., where he led ten acquisitions and over a dozen venture investments, including forming Helix and GRAIL. His investment thesis targets early-stage companies in genomics and precision health, with a geographic focus on advancing life sciences applications globally. The firm manages a $230 million fund and typically invests in sectors including life science tools, diagnostics, therapeutics, digital health, and agtech. While specific check sizes and lead/follow behavior are not explicitly detailed, Illumina Ventures has executed deals such as a $50 million equity investment in Alamar Biosciences in January 2026. Notable portfolio companies include Alamar Biosciences, DNA Script, Encoded Therapeutics, and Pattern Bioscience, with Naclerio serving on the boards of several, including Alamar and Pattern. Naclerio distinguishes himself through deep operational experience in genomics,
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