Jonathan E. Lim, M.D., is the Founder and Managing Partner of City Hill Ventures. See sector focus and contact routes.
Jonathan E. Lim, M.D., is the Founder and Managing Partner of City Hill Ventures, a San Diego-based venture capital firm he launched in December 2010 after emerging from a background as a physician and serial biotech entrepreneur. The firm’s investment thesis centers on mission-driven, early-stage opportunities in life sciences—including therapeutics, diagnostics, and medical devices—as well as healthcare technology, with expanded scope into cleantech and media & entertainment. City Hill typically invests seed to early-stage private companies, with historical check sizes ranging from $100,000 to $5 million, and Lim has directed these investments personally since the firm’s first fund closed in 2011. Notable portfolio companies include Erasca (co-founded by Lim and now his CEO role), Boundless Bio (where he serves as Chairman), and Ignyta (where he was former Chairman and CEO, later going public). Lim distinguishes himself as a physician-turned-venturepreneur who has founded or led three biotechs that reached public valuations over $1 billion, and he publicly frames his work as dedicated to “revitalizing people, planet and perspective” through health c
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