John Mandile is the Managing Director and founding partner of Sigma Prime Ventures. See sector focus and contact routes.
John Mandile is the Managing Director and founding partner of Sigma Prime Ventures, a Boston-based venture capital firm he co-founded with Paul Flanagan in 2012 after roughly two decades as an entrepreneur and business unit manager. The firm targets early-stage technology companies in SaaS, cloud, mobile, disruptive technologies, and technology-enabled services, with a geographic focus on the East Coast ecosystems of Boston, New York, and Atlanta. Sigma Prime typically invests check sizes between $500,000 and $10 million across Series A through C and later venture rounds, emphasizing Series A and Series B+ stages. Notable portfolio companies include Phenom People, BlueConic, NS1, aPriori Technologies, Ceros, and Nasuni, with a tracked $13 million Series B investment in BlueConic in January 2020. Mandile also serves as a founding partner of Social Ventures.org and holds board positions at organizations such as Health Leads, Densify, and Volt Active Data, where he chairs the board at Health Leads since 1997. The firm distinguishes itself by leveraging its partners' entrepreneurial pedigrees to provide both tactical and strategic guidance to emergin
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