Douglas G. Cole, M.D., is a Managing Partner at Flagship Pioneering who joined the Cambridge. See sector focus and contact routes.
Douglas G. Cole, M.D., is a Managing Partner at Flagship Pioneering who joined the Cambridge, MA-based venture creation firm in 2001 and focuses exclusively on life sciences. Before Flagship, he served as a Program Executive at Vertex Pharmaceuticals and an Instructor in Neurology at Harvard Medical School. Cole’s investment thesis centers on creating and developing breakthrough biotechnology, human health, and sustainable life science companies through Flagship’s proprietary venture creation model rather than traditional third-party investing. He has co-founded multiple notable companies including Moderna, Foghorn Therapeutics, Syros Pharmaceuticals, Ensemble Therapeutics, Inzen Therapeutics, Sigilon Therapeutics, and Denali Therapeutics. Cole typically leads venture creation efforts from inception, holding board director positions at public and private organizations such as Moderna, Foghorn Therapeutics, Sana Biotechnology, and Omega Therapeutics. While specific check sizes and lead/follow metrics for third-party deals are not publicly detailed, his distinctive point of view emphasizes building companies internally from scientific discovery rather tha
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